The effect of Tenecteplase on intravenous thrombus and retinal blood flow in patients with branch retinal vein occlusion (BRVO).

The Lions Eye Institute is currently seeking patients with a recent branch retinal vein occlusion to participate in a one month study. The T-BRVO study aims to show that an injection of Tenecteplase into the back of the eye (intraocular injection) will reduce the clot in the retinal vein and restore blood flow to the vein. It also aims to show that this treatment will result in improved vision outcomes. Participants will be assigned to receive the Tenecteplase injection or a sham injection one week before starting the current standard treatment of intraocular injections of anti-VEGF.

Trial Registry Number: ACTRN12615000185561

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