Vision is the most precious of our senses, yet our knowledge of many of the component processes of its development remains incomplete. The mature mammalian retina has a layered structure, with different neurons and glia cells organised into laminated layers.
This arises from the highly coordinated development of the retina where specific events require precise timing and spatial arrangements. Very little is known about the molecular mechanisms behind these events; more specifically, how cone photoreceptor migration during postnatal development proceeds and is regulated, and how it could be altered by disease.
Our research is directed towards establishing the basic cellular and molecular pathways behind cone photoreceptor migration that are activated in normal and degenerate retinas.
