Complementing our approach to community involvement is the Lions Eye Institute’s commitment to openness and ethical responsibility in all aspects of research.
As a signatory to the Openness Agreement on Animal Research and Teaching in Australia, the Lions Eye Institute is part of a national effort to promote transparency, public understanding, and accountability in animal-based research.
One important aspect of our ethical approach is the use of animal models in research. Animal models, such as mice and zebrafish, are essential for advancing our understanding of complex eye diseases like inherited retinal disease and myopia. These models allow us to study disease mechanisms and test new therapies, with the goal of preserving or restoring vision.
However, we recognise the significant responsibility that comes with conducting animal research. That’s why we adhere to strict ethical oversight, governed by the Animal Ethics Committees of The University of Western Australia and the Harry Perkins Institute of Medical Research. Additionally, we follow the Australian Code for the Care and Use of Animals for Scientific Purposes, set out by the National Health and Medical Research Council.
The zebrafish facility is enabling vital research into early-onset myopia
We also apply the 3Rs principles; internationally recognised guidelines that help ensure animal research is conducted with the utmost care and respect:
Replacement: Using alternate research methods without the use of animals where possible.
Reduction: Minimising the number of animals used in research.
Refinement: Continuously improving procedures to minimise harm and enhance animal welfare.
By being transparent about our animal research practices and the ethical safeguards in place, we aim to build public understanding and trust.
Through transparency and ethical responsibility, the Lions Eye Institute continues to drive research that makes a real difference, in both the lab and the lives of those living with vision conditions.
