Modern human neuroimaging offers unparalleled, non-invasive insights into the microstructural integrity of the living brain. The goal of this project is to harness the latest advancements in diffusion magnetic resonance imaging (MRI) to visualize and quantify differences in cortical microstructure between individuals with glaucoma and those without. This initiative is made possible by the recent installation of a state-of-the-art research-dedicated three-tesla MRI scanner at Level 3 of the Harry Perkins Institute of Medical Research, as part of the Western Australia National Imaging Facility node.
Glaucoma is increasingly recognized as having a profound impact on visual pathways beyond the eye, affecting both the optic tracts and the cortex—encompassing both the visual areas and more widespread regions. Understanding the extent of cortical damage caused by glaucoma is crucial for developing future neuroprotective treatments and gaining deeper insights into the disease’s effects on visual performance.
